chr21:47409531:G>A Detail (hg19) (COL6A1)
Information
Genome
Assembly | Position |
---|---|
hg19 | chr21:47,409,531-47,409,531 |
hg38 | chr21:45,989,617-45,989,617 View the variant detail on this assembly version. |
HGVS
Type | Transcript | Protein |
---|---|---|
RefSeq | NM_001848.2:c.868G>A | NP_001839.2:p.Gly290Arg |
Ensemble | ENST00000361866.8:c.868G>A | ENST00000361866.8:p.Gly290Arg |
Summary
MGeND
Clinical significance | |
Variant entry | |
GWAS entry | |
Disease area statistics | Show details |
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
Clinical significance | Last evaluated | Review status | Condition | Origin | Links |
---|---|---|---|---|---|
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2023-05-04 | criteria provided, multiple submitters, no conflicts | not provided |
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Detail |
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2023-10-04 | criteria provided, multiple submitters, no conflicts | Bethlem myopathy 1A |
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Detail |
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criteria provided, single submitter | Ullrich congenital muscular dystrophy 1A |
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Detail | |
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2018-08-24 | criteria provided, single submitter | Inborn genetic diseases |
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Detail |
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2021-07-10 | criteria provided, single submitter |
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Detail |
CIViC
[No Data.]
DisGeNET
Score | Disease name | Description | Source | Pubmed | Links |
---|---|---|---|---|---|
0.564 | Bethlem myopathy | NA | CLINVAR | Detail | |
0.368 | Scleroatonic muscular dystrophy | NA | CLINVAR | Detail | |
0.120 | Congenital muscular dystrophy (disorder) | NA | CLINVAR | Detail |
Annotation
Annotations
Descrption | Source | Links |
---|---|---|
NM_001848.3(COL6A1):c.868G>A (p.Gly290Arg) AND not provided | ClinVar | Detail |
NM_001848.3(COL6A1):c.868G>A (p.Gly290Arg) AND Bethlem myopathy 1A | ClinVar | Detail |
NM_001848.3(COL6A1):c.868G>A (p.Gly290Arg) AND Ullrich congenital muscular dystrophy 1A | ClinVar | Detail |
NM_001848.3(COL6A1):c.868G>A (p.Gly290Arg) AND Inborn genetic diseases | ClinVar | Detail |
NM_001848.3(COL6A1):c.868G>A (p.Gly290Arg) AND Abnormality of the musculature | ClinVar | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
---|
Overlapped Transcript
Gene | Transcript ID | Chromosome | Start | Stop | Links |
---|
- Gene
- -
- dbSNP
- rs121912939 dbSNP
- Genome
- hg19
- Position
- chr21:47,409,531-47,409,531
- Variant Type
- snv
- Reference Allele
- G
- Alternative Allele
- A
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